The beginning of immunity has been associated with the creation of man. A time when nature and wild animals were considered a threat to early humans. Early humans, like other creatures, instinctively avoided danger to save their animal lives. From the point of view of psychology, after physiological needs, the need for safety, like human instincts, is considered one of the most basic needs of man in the direction of his growth and prosperity. In the era when man's only tools were stone, wood, and bone, according to the type and nature of dangers, the method of avoiding them also changed, and mankind began preparing measures to deal with the dangers related to tools. Safety has been important since the beginning of human life on the planet and has changed shape throughout history. Knowing the history of safety in the world and in Iran can be a vision for the future. Humanity has been seeking effort and activity since the time it came to know itself, and naturally, it has gone through changes in the course of time. In the periods when human life is supported by hunting and fishing or agriculture, due to the simplicity of the tools, the complications related to the job (safety and health of the work environment) have been insignificant and in most cases from a few scratches with simple wounds to maximum broken limbs. It has not exceeded, but gradually as the industry progressed and mechanical and electric power came into existence, the risks also increased in the same proportion. With the occurrence of the industrial revolution in the years 1760 to 1830 in England and its spread to other European countries, the mechanical and electrical driving force was created. These transformations also had negative aspects, the most important of which are industrial accidents, noise, environmental pollution and air pollution. Regarding the prevention of industrial accidents, it should be acknowledged that mankind has accumulated a lot of painful experience.